How we pick our products
Welcome to our big inositol test 2022. Here we present all the inositol products that we have tested in detail. We have compiled detailed background information and added a summary of customer reviews on the internet.
We would like to make your purchase decision easier and help you find the best inositol for you.
You will also find answers to frequently asked questions in our guide. If available, we also offer interesting test videos. Furthermore, you will also find some important information on this page that you should definitely pay attention to if you want to buy an inositol product.
- 1 Summary
- 2 The Best Inositol: Our Picks
- 3 Guide: Questions you should ask yourself before buying inositol
- 4 Decision: What types of inositol are there and which is right for you?
- 5 Buying criteria: You can use these factors to compare and evaluate inositol
- 6 Interesting facts about inositol
- Inositol is a natural substance that occurs in humans, animals and plants. In smaller quantities, humans can even produce it themselves.
- Its effects are very diverse and can help with PCO, sleep disorders, depression, panic attacks, concentration problems, etc.
- Inositol beautifies the appearance of the skin and helps to maintain the splendour of the hair. By supporting the fat metabolism, it also stimulates digestion.
The Best Inositol: Our Picks
Guide: Questions you should ask yourself before buying inositol
What is inositol?
When less was known about inositol, it was defined as a vitamin and assigned to the group of B vitamins.
Due to its chemical molecular formula C6H12O6, we now know that it is a hexavalent cyclic alcohol.
Because of its vitamin-like substance, inositol also has a sweetness that makes this substance taste about half as sweet as our ordinary household sugar. Originally, inositol was therefore also known by the trivial name “muscle sugar”.
Besides the fact that inositol is found in various organisms as well as in our food, and plays an important role in numerous metabolic processes, it can even be produced by the human body itself in small quantities. This finding was clear proof that inositol is not a vitamin.
In total, inositol can occur in nine different forms (isomers). Relevant of these are myo-inositol, which occurs predominantly in our body and can also be produced by ourselves.
Furthermore, D-chiro-inositol plays an important role from a nutritional-physiological point of view. The actual effects of the other seven have not yet been sufficiently researched.
For whom is inositol suitable?
Basically, taking inositol is a way of supplying your body with the amounts it cannot produce itself.
Inositol is a natural messenger substance that the body needs to control all processes, such as metabolism, hormone balance, etc. Inositol is a natural messenger substance that the body needs to control all processes, such as metabolism, hormone balance, etc. Inositol is a natural messenger substance.
Since inositol occurs several times in the human organism, it can be taken in the recommended daily dose without any problems. This is especially true if you have a deficiency, and the intake of inositol can have clearly positive effects.
However, you should always stick to the recommended daily dose, as side effects from an overdose of inositol have not yet been researched.
Pregnant women in particular should take care to avoid larger amounts, as it could possibly cause contractions of the uterus (labour pains).
What is treated with inositol?
Patients with PCO syndrome
Inositol is mainly used to treat women with PCO syndrome (polycystic ovary syndrome). This is a disease characterised by cycle disorders, elevated hormone levels and ovarian cysts, etc.
Due to this syndrome, those patients are usually unable to have children naturally, as the causes of PCO have not yet been clarified. Currently, the only thing that can be done is to alleviate the associated symptoms.
In various studies, it has been proven that inositol has led to an improved quality of the eggs in the test persons after five to six months of taking the substance and that an increased volume of the ovaries could also be significantly reduced.
Many women who tested inositol also reported that they had more regular periods and less pain.
Another aspect is that inositol also reduces insulin resistance, a common side effect of PCO, which is also important for diabetics.
Inositol for sleep disorders, panic attacks and depression
It has also been shown that inositol has a positive effect on the mind. It contributes to the fact that depressions and panic attacks occur less frequently and are considerably less intense. (1)
This was observed by showing a comparable effect with antidepressants, but in a natural way.
Here again, it must also be mentioned that inositol is only a food supplement and treatment in chronic cases must always be discussed with the doctor beforehand.
Inositol also has a supportive effect on sleep disorders, as it helps to calm the mood and establish inner peace.
Your body needs myo-inositol for the transmission of information in the brain.
It is therefore advisable to take inositol as you get older to support your memory and prevent a decline in performance.
Children and adolescents in particular are often affected by concentration difficulties when learning. Here, too, inositol can be a remedy to achieve better learning results in the long term through upright concentration.
What else is inositol helpful for?
Inositol is also important for hair growth and healthy skin, and can help with acne, for example. It also plays an important role in fertility, muscle activity and bone marrow.
It is also thought to support weight loss by stimulating the metabolism.
Inositol is also therapeutic in patients with bulimia nervosa and binge eating disorder, as well as in patients with depression and panic and obsessive-compulsive disorders. This increases its parallelism with serotonin-selective reuptake inhibitors. (2)
Type 2 diabetes
In 2016, a pilot study was also published that investigated the effectiveness and safety of myo-inositol and D-chiro-inositol in type 2 diabetes patients. After three months, fasting blood glucose and HbA1c leves were shown to have decreased significantly.
In summary, the study leaders descripe the dietary supplements of myo-inositol and D-chiro-inositol as an effective and safe option to improve glycaemic control in type 2 diabetes. (3)
In 1996, a study was already carried out to investigate the effects of treatment with inositol with Alzheimer’s patients. The patients were given 6 gm of inositol per day or daily glucose over a period of one month.
Speech and orientation improved significantly in the inositol group.
There were no serious side effects. The study leaders recommend that higher doses of inositol in connection with Alzheimer’s disease be investigated in further studies over a longer period of time. (4)
How does inositol work?
For example, this substance stabilises and protects the cell membrane and also transmits signals between the cells.
The highest concentrations of myo-inositol are found in the muscles, heart and brain. The substance promotes muscle growth, which is why athletes and bodybuilders often use this food supplement.
In the cell membrane itself, inositol anchors the proteins and ensures the regulation of the calcium and sodium flow through the cell walls.
Furthermore, myo-inositol is responsible for the regulation of fat metabolism as well as fat excretion by the liver.
In the brain and nerve fibres, the substance plays an important role in the transmission of nerve impulses. As already mentioned, inositol also has a relaxing effect, which can help you fall asleep.
Myo-inositol is also found in larger quantities in the testicles, as it is needed for the production and maturation of sperm.
A deficiency of this substance could lead to hair loss, growth disorders or even fatty liver, among other things, as has already been proven in animal studies.
How is inositol dosed and taken?
For D-Chiro-Inositol, a lower dosage is sufficient. In studies, subjects were given between 100 mg and over 1000 mg daily. Here, however, the actual optimum would already be a daily dose of 200 mg to 500 mg.
|2000-3000 mg daily||200-500 mg daily|
According to the results of the studies, it makes even more sense to combine the two types of inositol to achieve an even better effect.
For women who want to have children, it is also recommended to take alpha-lipoic acid, antioxidants and a vitamin complex with folic acid.
However, you are always on the safe side if you follow the recommended daily dose according to the package insert.
Inositol powder dissolves well in water and can be taken as is or with fruit juices or smoothies. It can also be swallowed in capsule form with water.
How long should inositol be taken?
However, there were also women who noticed positive changes after only two months.
It also depends on the person themselves how well and quickly the inositol works. Too much coffee can significantly reduce the effect, as it partially destroys the substance. Also, too much water consumption (2.5 litres and more) makes your body excrete the inositol again unused.
Certain medications and also the lack of important vitamins, nutrients, trace elements and the like can impair the effect of inositol. In such cases, it is advisable to consult a doctor.
Are there any side effects when taking inositol?
In general, the answer to this question is no, as hardly any side effects have occurred so far. However, it is not advisable to exceed the recommended daily dose.
It is still unclear whether an overdose can lead to side effects. For pregnant women, however, it is especially recommended that the daily dose be taken as a maximum and never more.
What alternatives are there to inositol?
Since the PCO syndrome is often also characterised by disturbances in the sugar metabolism, the diabetes drug metformin is intended as a remedy. It acts primarily on the elevated blood sugar, but also on hormones, and achieves comparable results to Myo-Inositol.
Decision: What types of inositol are there and which is right for you?
If you want to get inositol, there are two main options to choose between:
- Myo-Inositol with other substances
The different types each come with advantages and disadvantages. Depending on what you prefer, a different type may be right for you. The following section is designed to help you decide.
What is myo-inositol and what are the advantages and disadvantages?
Myo-inositol is the most abundant form, and the one with the most research and studies to date. If you buy pure inositol, it is almost always this form.
What distinguishes Myo-Inositol from other substances and what are the advantages and disadvantages ?
D-Chiro-Inositol is the second most commonly used form, which has also been well researched. According to studies, even better results were obtained when the two forms, myo-inositol and D-chiro-inositol, were combined.
Especially in PCO patients who wanted to have children, this had a positive effect when the combination was supplemented with folic acid. Folic acid is a water-soluble vitamin, of which too little is often supplied in the diet. During pregnancy, it helps to prevent malformations.
A combination of inositol and choline is also recommended. Together they form lecithin. This substance prevents hair loss, strengthens hair growth and helps with eczema. Choline also metabolises fat and cholesterol and is involved in the formation of new nerve cells.
However, it must also be said that those side effects occur only very rarely, as such an overdose is highly unlikely.
Prior consultation with the doctor or orientation on the recommended daily dose is always advisable.
Buying criteria: You can use these factors to compare and evaluate inositol
In the following, we would like to show you which factors you can use to compare and evaluate inositol products. This will make it easier for you to decide whether a particular inositol is suitable for you or not.
In summary, these are:
- Capsule or powder form
- Recommended daily dose
- Notes on production
Capsule or powder form
It is up to you to decide which you prefer. However, capsules are the easiest to handle, as the exact dosage is already given and the respective number of capsules only needs to be taken with water.
Inositol powder really has to be dosed precisely. Details are always available in the product description. It is worth buying a precision scale that gives the exact milligrams. You can buy such a scale for an average of €10 on Amazon, for example.
In order to get the best deal, you should compare the quantities of the packs and calculate which one will last you the longest.
For example, if you buy a 250 g package of inositol powder, you would last 100 days with an average daily dose of 2.5 g.
Then you can compare whether the powder or the capsules are cheaper. Then, of course, you have to compare the prices of the different suppliers.
This point is especially important if you are a vegetarian or vegan. Many food supplements still contain animal gelatine, which is why it is always worth taking a look at the ingredients beforehand.
Allergies to inositol are not known so far. However, you might not tolerate another substance in a combination preparation, which is why you should also check the contents beforehand.
Recommended daily dose
As already mentioned several times, it is best to follow the recommended daily dose. More detailed information can be found above or in the package leaflet of the respective product.
You should take the inositol for several weeks to see the results.
Tips for production
When manufacturing inositol, it is important to know how and where it was produced.
German pharmacy manufacturers and laboratories, for example, are subject to strict guidelines, and quality always plays the most important role. In any case, you should attach importance to this.
Some suppliers do not use unnecessary packaging material, which is also good for the environment.
Interesting facts about inositol
Which foods contain inositol?
In our food, inositol is found in large quantities in wheat products. It can also be found in beans, nuts, almonds or popcorn.
If you like to eat fruit, you should eat melons, oranges, grapefruit, kiwis, nectarines, mango or pears.
If you drink a lot of alcohol or caffeinated drinks, you will destroy most of the inositol in your body, which can cause a deficiency.
What are the properties of inositol in cosmetics?
Inositol also has a positive effect on beauty. That is why many cosmetic products contain this substance. It has been proven to have a skin-smoothing and wrinkle-reducing effect.
Inositol also moisturises and has an antistatic effect. It is therefore contained in many skin and hair care products.
Whether discount or expensive brand-name products, inositol is also very popular in the cosmetics industry.
Photo source: 123rf.com / Rattanaburi V.
A Palatnik, K Frolov, M Fux, J Benjamin. Double-blind, Controlled, Crossover Trial of Inositol Versus Fluvoxamine for the Treatment of Panic Disorder. J Clin Psychopharmacol. Jun 2001; 21 (3), 335-9.
D Gelber , J Levine, R H Belmaker. Effect of Inositol on Bulimia Nervosa and Binge Eating. Int J Eat Disord. Apr 2001; 29 (3), 345-8.
Basilio Pintaudi, Giacoma Di Vieste, Matteo Bonomo. The Effectiveness of Myo-Inositol and D-Chiro Inositol Treatment in Type 2 Diabetes. Int J Endocrinol. 2016; 2016: 9132052.
Y Barak, J Levine, A Glasman, A Elizur, R H Belmaker. Inositol Treatment of Alzheimer's Disease: A Double Blind, Cross-Over Placebo Controlled Trial. Prog Neuropsychopharmacol Biol Psychiatry. May 1996; 20 (4), 729-35.